Opportunity Information: Apply for HT9425 23 MRP FPA RM
The Department of Defense Melanoma Research Program (MRP) is offering the FY23 Melanoma Focused Program Award - Rare Melanomas (FPA-RM) to fund a coordinated, multidisciplinary research effort aimed specifically at rare forms of melanoma. This opportunity is designed to support a tightly integrated research program made up of at least two and no more than three distinct projects that work together toward a shared scientific goal. Rather than funding a single standalone study, the program emphasizes a package of complementary projects that collectively tackle a major problem in rare melanoma research or patient care.
A central requirement of the FPA-RM is the presence of a clear, unifying overarching question. Applicants must define one big question that links all proposed projects and demonstrates how the combined program will address a critical unmet need in rare melanomas. The overarching question can be tailored to one rare melanoma subtype or be framed broadly to address a need that cuts across multiple rare melanoma types. The solicitation highlights rare melanoma contexts such as uveal, acral, mucosal, and pediatric melanoma as examples of the intended focus. The key idea is that the projects should not feel like separate efforts bundled together; they should be designed to inform one another and collectively deliver a more complete answer than any single project could provide alone.
The scope of research topics is intentionally broad, allowing applicants to propose projects anywhere across the research and care continuum. Proposed work can span fundamental biology, causes and risk factors (etiology), prevention approaches, improved diagnosis and detection, prognostic tools, treatment strategies, and quality-of-life research. Regardless of the specific area, the application must make a strong case that the work targets a meaningful gap or urgent challenge in rare melanoma science and/or clinical management, and that the proposed multi-project structure is essential to achieving the program goals.
There is also a clear boundary on what is not allowed: studies involving non-melanoma skin cancers are explicitly prohibited under this FY23 MRP opportunity. Applicants need to ensure the scientific aims, samples, models, and clinical populations are aligned with rare melanoma and do not drift into other skin cancer categories that fall outside the program.
From an administrative standpoint, this is a Department of Defense funding opportunity managed by the U.S. Army Medical Research Acquisition Activity (USAMRAA). The opportunity number is HT9425 23 MRP FPA RM, and it falls under CFDA 12.420. The funding mechanism includes cooperative agreements and grants, and eligibility is described as unrestricted, meaning applications are generally open to a wide range of organization types as permitted by any additional eligibility language in the full announcement. The posting date is May 18, 2023, with an original closing date of September 22, 2023. The opportunity indicates an expected total of two awards, and the listed award ceiling is shown as 0 in the provided source data, which typically signals that applicants should rely on the full funding announcement for any specific budget limits or that ceiling information was not populated in the summary fields.
Overall, this award is aimed at teams that can build an integrated mini-portfolio of projects around one coherent question, with the explicit goal of advancing understanding and improving outcomes in rare melanoma types where major clinical and scientific needs remain unmet.Apply for HT9425 23 MRP FPA RM
- The Department of Defense, Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Melanoma Focused Program Award - Rare Melanomas" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
- This funding opportunity was created on May 18, 2023.
- Applicants must submit their applications by Sep 22, 2023. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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FAQs: FY23 Melanoma Focused Program Award - Rare Melanomas (FPA-RM)
What is the FY23 Melanoma Focused Program Award - Rare Melanomas (FPA-RM)?
The FY23 Melanoma Focused Program Award - Rare Melanomas (FPA-RM) is a Department of Defense Melanoma Research Program (MRP) funding opportunity intended to support a coordinated, multidisciplinary research effort focused specifically on rare forms of melanoma. It is structured to fund an integrated program made up of multiple interrelated projects rather than a single standalone study.
What is the main goal of this award?
The main goal is to fund a tightly integrated set of projects that collectively address a critical unmet need in rare melanoma research and/or patient care. The program is designed so that the combined work produces a more complete answer than any single project could deliver on its own.
How many projects must be included in an application?
Applications must include at least two and no more than three distinct projects. These projects are expected to operate as a coordinated package, working together toward a shared scientific goal.
Do the projects need to be connected to each other?
Yes. The opportunity emphasizes that the projects should not feel like separate efforts bundled together. They should be designed to inform one another and collectively advance a unified program objective.
Is an overarching question required?
Yes. A central requirement is a clear, unifying overarching question that links all proposed projects. Applicants must define one "big question" and show how the integrated program will address an important gap or urgent challenge in rare melanomas.
Can the overarching question focus on a single rare melanoma subtype?
Yes. The overarching question can be tailored to one rare melanoma subtype.
Can the overarching question address multiple rare melanoma types?
Yes. The overarching question can also be framed broadly to address a need that cuts across multiple rare melanoma types.
Which rare melanoma contexts are specifically highlighted?
The solicitation highlights rare melanoma contexts such as uveal, acral, mucosal, and pediatric melanoma as examples of the intended focus.
What research areas or topics are allowed under this opportunity?
The scope is intentionally broad and can include work across the research and care continuum. Examples of allowable areas include fundamental biology, causes and risk factors (etiology), prevention approaches, improved diagnosis and detection, prognostic tools, treatment strategies, and quality-of-life research.
Does the program require the research to address a specific type of study (basic vs. clinical)?
No. Based on the provided information, the program allows proposals across the continuum, from fundamental biology through clinical management topics and quality-of-life research, as long as the focus is rare melanoma and the multi-project structure is essential to the goals.
What is explicitly not allowed under this funding opportunity?
Studies involving non-melanoma skin cancers are explicitly prohibited. Applicants need to ensure that scientific aims, samples, models, and clinical populations stay aligned with rare melanoma and do not drift into other skin cancer categories.
Who is offering and managing this grant opportunity?
This is a Department of Defense funding opportunity under the Melanoma Research Program (MRP), managed by the U.S. Army Medical Research Acquisition Activity (USAMRAA).
What is the opportunity number for this solicitation?
The opportunity number is HT9425 23 MRP FPA RM.
What is the CFDA number associated with this opportunity?
The opportunity is listed under CFDA 12.420.
What funding mechanisms are included?
The funding mechanism includes cooperative agreements and grants.
Who is eligible to apply?
Eligibility is described as unrestricted, meaning applications are generally open to a wide range of organization types, as permitted by any additional eligibility language in the full announcement.
When was this opportunity posted?
The posting date is May 18, 2023.
What is the closing date for applications?
The original closing date is September 22, 2023.
How many awards does the program expect to make?
The opportunity indicates an expected total of two awards.
What is the maximum award amount (award ceiling)?
In the provided source data summary fields, the award ceiling is shown as 0. This commonly indicates that applicants should rely on the full funding announcement for any specific budget limits, or that ceiling information was not populated in the summary.
What does "focused program" mean in practice for applicants?
In practice, it means proposing an integrated mini-portfolio of 2-3 complementary projects organized around one coherent overarching question. The application should clearly justify why the multi-project structure is necessary and how the projects collectively address a major problem or unmet need in rare melanoma.
What should applicants be careful about when defining the research scope?
Applicants should ensure that the full program stays focused on rare melanomas and does not include non-melanoma skin cancer studies, including in the choice of models, samples, or clinical populations.
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