Opportunity Information: Apply for W81XWH 21 NFRP SIA
The Department of Defense Neurofibromatosis Research Program (NFRP) Synergistic Idea Award is a discretionary research funding opportunity administered by the Department of Defense, Department of the Army, through USAMRAA. It is aimed at advancing neurofibromatosis (NF) research by supporting projects built around genuinely collaborative, synergy-driven concepts rather than single-lab efforts. The core premise is that certain NF problems are best tackled when multiple investigators combine distinct expertise, approaches, and ways of thinking to produce outcomes that would be difficult to achieve independently.
This award specifically requires a team-based structure led by two or three Principal Investigators (PIs). The expectation is that the investigators bring complementary strengths and integrate their perspectives in a way that directly serves a shared central problem or research question in NF. In other words, the work should not look like separate subprojects loosely bundled together; it should read as an intentionally coordinated effort where the collaboration itself is essential to the scientific strategy and the anticipated advances. The program allows for both new collaborations and established partnerships, recognizing that either can produce strong synergy when the scientific fit is right.
A notable feature of the opportunity is its encouragement of participation from PIs outside the traditional NF research community. This is meant to draw in methods, technologies, and conceptual frameworks from other fields that could unlock new angles on NF biology, diagnosis, treatment, or disease management. In practice, that could mean pairing NF specialists with experts in areas like genomics, immunology, bioengineering, computational biology, imaging, drug delivery, or other adjacent disciplines, as long as the combined expertise is clearly aligned to an NF-focused objective.
From an administrative and funding standpoint, the opportunity (Funding Opportunity Number W81XWH 21 NFRP SIA) supports projects through either a grant or a cooperative agreement mechanism, both categorized under science and technology and other research and development. Eligibility is described as unrestricted, meaning a wide range of entity types may apply, subject to any additional eligibility clarifications contained in the full announcement. The listing notes an expected number of awards of 1. The award ceiling is listed as 0, which typically signals that the specific maximum funding level may be defined elsewhere in the full program announcement or may depend on the proposed scope, rather than being stated in the summary field.
Key dates included in the public listing show a creation date of April 30, 2021, with an original closing date of July 22, 2021. Overall, the Synergistic Idea Award is best understood as a mechanism for funding high-value NF research questions where progress depends on tight, well-justified collaboration among two or three PIs, including teams that intentionally bridge NF research with outside disciplines to generate new ideas and more powerful combined approaches.Apply for W81XWH 21 NFRP SIA
- The Department of Defense, Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DOD Neurofibromatosis, Synergistic Idea Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
- This funding opportunity was created on Apr 30, 2021.
- Applicants must submit their applications by Jul 22, 2021. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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FAQs: DoD Neurofibromatosis Research Program (NFRP) Synergistic Idea Award
What is the NFRP Synergistic Idea Award?
The Neurofibromatosis Research Program (NFRP) Synergistic Idea Award is a discretionary Department of Defense research funding opportunity administered by the Department of Defense, Department of the Army, through USAMRAA. It is designed to advance neurofibromatosis (NF) research by supporting projects that are built around genuine collaboration and scientific synergy rather than single-lab efforts.
What is the main purpose of this award?
The central purpose is to fund NF research questions where meaningful progress is most likely when multiple investigators combine distinct expertise, approaches, and ways of thinking to achieve outcomes that would be difficult to accomplish independently.
What kind of project structure does this award require?
This award requires a team-based structure led by two or three Principal Investigators (PIs). The project should be organized around a shared central NF problem or research question, with investigators contributing complementary strengths in a tightly integrated way.
How many Principal Investigators (PIs) are required?
Applicants must propose a team led by two or three PIs. A single-PI structure does not match the stated requirement for this opportunity.
What does "synergy-driven" collaboration mean in this opportunity?
Are new collaborations allowed, or does the team need an established partnership?
Both new collaborations and established partnerships are allowed. The program recognizes that either can produce strong synergy when the scientific fit and integrated plan are well justified.
Does the award encourage participation from researchers outside the traditional NF research community?
Yes. A notable feature of this opportunity is that it encourages participation from PIs outside the traditional NF research community, with the goal of bringing in methods, technologies, and conceptual frameworks from other fields to open new angles on NF research.
What types of outside disciplines might be relevant to an NF-focused team?
The listing gives examples such as genomics, immunology, bioengineering, computational biology, imaging, drug delivery, and other adjacent disciplines, as long as the combined expertise is clearly aligned to an NF-focused objective.
What scientific areas of NF research could a project address?
Based on the description, projects may focus on NF biology, diagnosis, treatment, or disease management, provided the work remains centered on an NF problem and the synergy between the two or three PIs is clearly essential to the research strategy.
Who administers this funding opportunity?
The award is administered by the Department of Defense, Department of the Army, through USAMRAA (as stated in the opportunity description).
What is the Funding Opportunity Number for this award?
The Funding Opportunity Number is W81XWH 21 NFRP SIA.
What funding mechanisms are used for this opportunity?
The opportunity supports projects through either a grant or a cooperative agreement mechanism. Both are categorized under science and technology and other research and development in the listing.
What does "eligibility is unrestricted" mean here?
The listing describes eligibility as unrestricted, meaning a wide range of entity types may apply. However, the description also notes that any additional eligibility clarifications would be contained in the full announcement.
How many awards are expected to be made?
The listing notes an expected number of awards of 1.
Is there a maximum funding amount (award ceiling) stated in the listing?
The award ceiling is listed as 0. The description indicates this typically means the specific maximum funding level may be defined elsewhere in the full program announcement or may depend on the proposed scope rather than being stated in the summary field.
What are the key dates shown for this opportunity?
The public listing shows a creation date of April 30, 2021, and an original closing date of July 22, 2021.
What is the overall emphasis reviewers are likely to look for based on the description?
Based on the information provided, the emphasis is on a tightly integrated, genuinely collaborative plan led by two or three PIs with complementary expertise, where the collaboration is essential to solving a central NF research question and is likely to produce advances that would be difficult to achieve through independent efforts.
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| DOD Neurofibromatosis, Exploration-Hypothesis Development Award Apply for W81XWH 21 NFRP EHDA Funding Number: W81XWH 21 NFRP EHDA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DOD Neurofibromatosis, Clinical Trial Award Apply for W81XWH 21 NFRP CTA Funding Number: W81XWH 21 NFRP CTA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
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| DOD Melanoma Mid-Career Accelerator Award Apply for W81XWH 21 MRP MCAA Funding Number: W81XWH 21 MRP MCAA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DOD Melanoma Melanoma Academy Leadership Award Apply for W81XWH 21 MRP MALA Funding Number: W81XWH 21 MRP MALA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DOD Melanoma Team Science Award Apply for W81XWH 21 MRP TSA Funding Number: W81XWH 21 MRP TSA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DOD Melanoma Translational Research Award Apply for W81XWH 21 MRP TRA Funding Number: W81XWH 21 MRP TRA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DOD Melanoma Melanoma Academy Scholar Award Apply for W81XWH 21 MRP MASA Funding Number: W81XWH 21 MRP MASA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DOD Melanoma Idea Award Apply for W81XWH 21 MRP IA Funding Number: W81XWH 21 MRP IA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| FY21 DEFENSE ESTABLISHED PROGRAM TO STIMULATE COMPETITIVE RESEARCH (DEPSCoR) – RESEARCH COLLABORATION (RC) Apply for FOA AFRL AFOSR 2021 0007 Funding Number: FOA AFRL AFOSR 2021 0007 Agency: Department of Defense, Air Force Office of Scientific Research Category: Science and Technology and other Research and Development Funding Amount: $600,000 |
| DOD Multiple Sclerosis Clinical Trial Award Apply for W81XWH 21 MSRP CTA Funding Number: W81XWH 21 MSRP CTA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DOD Multiple Sclerosis Exploration - Hypothesis Development Award Apply for W81XWH 21 MSRP EHDA Funding Number: W81XWH 21 MSRP EHDA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
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