Opportunity Information: Apply for RFA ES 18 010
This funding opportunity (RFA-ES-18-010) is a National Institutes of Health (NIH) cooperative agreement (U24; clinical trial not allowed) focused on building and running the central coordinating hub for the Human Health Exposure Analysis Resource (HHEAR). HHEAR is described as the next phase and broader continuation of the Children’s Health Exposure Analysis Resource (CHEAR). The larger purpose of the HHEAR consortium is to make it easier for biomedical and public health researchers to incorporate high-quality environmental exposure measurements into their studies by giving them access to specialized laboratory assays and statistical analysis support. A major emphasis is that the exposure data generated through this resource should be made publicly available, strengthening the evidence base on how environmental exposures affect health across the full life course, rather than only in childhood.
The specific award supported by this announcement is for the HHEAR Coordinating Center, which functions as the administrative hub and the primary external “front door” for investigators who want to use HHEAR services. In practical terms, the coordinating center is expected to manage, monitor, and document the end-to-end movement of projects through the HHEAR system: intake and tracking of requests, coordination of communications among participating investigators and the various HHEAR units, and oversight of the logistics around materials and samples, analytic workflows, and resulting datasets. Because the mechanism is a cooperative agreement, the project is meant to be run in close partnership with NIH program staff, with substantial NIH involvement typical of U-series awards.
Beyond operational tracking, the coordinating center is also responsible for consortium-wide administration and community-facing activities. That includes organizing and supporting meetings of key governance bodies such as the HHEAR Steering Committee and Executive Committee, preparing meeting materials, documenting decisions, and helping ensure that consortium activities stay aligned with agreed priorities and timelines. The center is also tasked with education, outreach, and publicity, which generally means communicating what HHEAR offers, helping researchers understand how to apply for services, and promoting awareness and appropriate use of the resource. Taken together, the coordinating center role is less about conducting independent bench science and more about building a reliable, transparent, and responsive infrastructure that enables many other studies to add rigorous exposure assessment.
The opportunity is categorized under environment and health (CFDA 93.113) and is open to a wide range of applicant organization types. Eligible applicants listed include state, county, city or township governments, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations other than federally recognized tribal governments; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (excluding institutions of higher education); for-profit organizations other than small businesses; small businesses; and additional eligible entities. The announcement also calls out other eligible applicant groups such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions.
At the same time, the eligibility language places clear limits on non-U.S. applicants. Non-domestic (non-U.S.) entities and non-domestic components of U.S. organizations are not eligible to apply as the applicant organization. However, “foreign components” are allowed as defined by the NIH Grants Policy Statement, meaning a U.S.-based applicant could still include certain foreign elements in the overall project structure if they meet NIH’s definition and requirements for foreign components.
Key administrative details provided include an original closing date of October 29, 2018, and an award ceiling of $700,000. The main idea is that NIH, led by the National Institute of Environmental Health Sciences (NIEHS) with partnering NIH Institutes and Centers, is funding a central coordinating operation that keeps HHEAR functioning smoothly as a national resource: a place where environmental exposure measurement and analytic capacity can be efficiently connected to diverse health studies, with outputs that ultimately become a public data asset for the broader research community.Apply for RFA ES 18 010
- The National Institutes of Health in the environment, health sector is offering a public funding opportunity titled "Human Health Exposure Analysis Resource: Coordinating Center (U24 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113.
- This funding opportunity was created on 2018-08-30.
- Applicants must submit their applications by 2018-10-29. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $700,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs)
What is the funding opportunity number and what does it support?
This opportunity is RFA-ES-18-010. It supports an NIH cooperative agreement (U24; clinical trial not allowed) to build and run the central coordinating hub for the Human Health Exposure Analysis Resource (HHEAR), specifically the HHEAR Coordinating Center.
What is HHEAR?
HHEAR stands for the Human Health Exposure Analysis Resource. It is described as the next phase and broader continuation of the Children’s Health Exposure Analysis Resource (CHEAR). Its purpose is to make it easier for biomedical and public health researchers to incorporate high-quality environmental exposure measurements into their studies by providing access to specialized laboratory assays and statistical analysis support.
How is HHEAR related to CHEAR?
HHEAR is described as the next phase and a broader continuation of CHEAR (the Children’s Health Exposure Analysis Resource). A key shift emphasized is strengthening evidence on how environmental exposures affect health across the full life course, not only in childhood.
What is being funded under this announcement?
This announcement funds the HHEAR Coordinating Center. The Coordinating Center functions as the administrative hub of the HHEAR consortium and serves as the primary external "front door" for investigators who want to use HHEAR services.
What does "Coordinating Center" mean in practical terms for this program?
The Coordinating Center is expected to manage, monitor, and document the end-to-end movement of projects through the HHEAR system. This includes intake and tracking of requests; coordinating communications among investigators and HHEAR units; and overseeing logistics related to materials and samples, analytic workflows, and the resulting datasets.
Is this award primarily for conducting independent laboratory or bench research?
No. The Coordinating Center role is described as being less about conducting independent bench science and more about building a reliable, transparent, and responsive infrastructure that enables many other studies to add rigorous exposure assessment.
What type of NIH award mechanism is this?
It is an NIH cooperative agreement using the U24 mechanism.
What does it mean that this is a cooperative agreement (U24)?
Because the mechanism is a cooperative agreement, the project is meant to be run in close partnership with NIH program staff, with substantial NIH involvement typical of U-series awards.
Are clinical trials allowed under this opportunity?
No. The announcement specifies "clinical trial not allowed."
Who leads this NIH effort?
NIH, led by the National Institute of Environmental Health Sciences (NIEHS) with partnering NIH Institutes and Centers, is funding the Coordinating Center as part of keeping HHEAR functioning smoothly as a national resource.
What are the main goals of the overall HHEAR consortium?
The consortium aims to lower barriers for researchers to include high-quality environmental exposure measurements in their studies by connecting them to specialized laboratory assays and statistical analysis support. A major emphasis is that the exposure data generated should be made publicly available to strengthen the evidence base on environmental exposures and health across the life course.
What does the Coordinating Center do as the "front door" for investigators?
As the primary external entry point, the Coordinating Center handles intake and tracking of requests from investigators who want to use HHEAR services and coordinates communications and processes across the HHEAR system.
What kinds of project flow or lifecycle activities does the Coordinating Center oversee?
Based on the description, the center oversees end-to-end project movement through HHEAR, including request intake, tracking, coordination across HHEAR units, and logistics surrounding materials and samples, analytic workflows, and resulting datasets.
What consortium-wide governance support is expected from the Coordinating Center?
The center is responsible for organizing and supporting meetings of key governance bodies such as the HHEAR Steering Committee and Executive Committee, preparing meeting materials, documenting decisions, and helping keep consortium activities aligned with agreed priorities and timelines.
What education, outreach, and publicity responsibilities are included?
The Coordinating Center is tasked with education, outreach, and publicity activities. This generally includes communicating what HHEAR offers, helping researchers understand how to apply for services, and promoting awareness and appropriate use of the resource.
What is expected regarding data sharing or public availability of outputs?
A major emphasis is that exposure data generated through HHEAR should be made publicly available, strengthening the evidence base on how environmental exposures affect health across the full life course.
What is the CFDA number and topic area for this opportunity?
The opportunity is categorized under environment and health and is listed as CFDA 93.113.
What is the award ceiling mentioned for this announcement?
The award ceiling provided is $700,000.
What was the original closing date listed?
The original closing date provided is October 29, 2018.
What types of organizations are eligible to apply?
The opportunity is open to a wide range of applicant organization types, including various government entities (state, county, city or township, and special district governments), independent school districts, public and state-controlled institutions of higher education, private institutions of higher education, federally recognized Native American tribal governments, other tribal organizations, public housing authorities/Indian housing authorities, nonprofits with or without 501(c)(3) status (excluding institutions of higher education), for-profit organizations other than small businesses, small businesses, and additional eligible entities.
Are institutions serving specific communities explicitly mentioned as eligible?
Yes. The eligibility language calls out Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISIs); Hispanic-serving institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); and faith-based or community-based organizations, among others.
Are U.S. territories or possessions eligible?
Yes. The announcement lists U.S. territories or possessions among other eligible applicant groups.
Can federal agencies apply?
The announcement includes "eligible federal agencies" among other eligible applicant groups.
Are non-U.S. (non-domestic) organizations eligible to apply as the applicant?
No. Non-domestic (non-U.S.) entities and non-domestic components of U.S. organizations are not eligible to apply as the applicant organization.
Are any foreign activities allowed at all under this opportunity?
Yes, limited foreign involvement may be included through "foreign components" as defined by the NIH Grants Policy Statement. This means a U.S.-based applicant could include certain foreign elements if they meet NIH's definition and requirements for foreign components.
What is the central value proposition of this Coordinating Center award?
The central idea is to fund a national coordinating operation that keeps HHEAR functioning smoothly as a resource that efficiently connects environmental exposure measurement and analytic capacity to diverse health studies, with outputs that ultimately become a public data asset for the broader research community.
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Applicants also applied for:
Applicants who have applied for this opportunity (RFA ES 18 010) also looked into and applied for these:
| Funding Opportunity |
|---|
| Human Health Exposure Analysis Resource: UnTargeted Exposure Analysis Laboratories (U2C Clinical Trial Not Allowed) Apply for RFA ES 18 012 Funding Number: RFA ES 18 012 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $1,500,000 |
| Human Health Exposure Analysis Resource: Targeted Exposure Analysis Laboratories (U2C Clinical Trial Not Allowed) Apply for RFA ES 18 011 Funding Number: RFA ES 18 011 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $1,500,000 |
| Human Health Exposure Analysis Resource: Environmental Exposure Analysis Laboratories (U2C Clinical Trial Not Allowed) Apply for RFA ES 18 013 Funding Number: RFA ES 18 013 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $700,000 |
| Maintain and Enrich Resource Infrastructure for Existing Environmental Epidemiology Cohorts (R24 Clinical Trial Not Allowed) Apply for RFA ES 18 009 Funding Number: RFA ES 18 009 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $250,000 |
| Virtual Consortium for Translational/Transdisciplinary Environmental Research (ViCTER) (R01 Clinical Trial Optional) Apply for RFA ES 18 007 Funding Number: RFA ES 18 007 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $400,000 |
| Enhancing Data Management and Sharing in NIEHS-Funded Research Grants (Admin Supp Clinical Trial Not Allowed) Apply for PA 19 025 Funding Number: PA 19 025 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $75,000 |
| Early Screening for Autism Spectrum Disorder (R01 Clinical Trial Not Allowed) Apply for RFA MH 19 120 Funding Number: RFA MH 19 120 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $500,000 |
| Immuno-Oncology Translation Network (IOTN): Cancer Immunoprevention Research Projects (U01 Clinical Trial Not Allowed) Apply for RFA CA 19 014 Funding Number: RFA CA 19 014 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $500,000 |
| Immuno-Oncology Translation Network (IOTN): Cancer Immunotherapy Research Projects (U01 Clinical Trial Not Allowed) Apply for RFA CA 19 015 Funding Number: RFA CA 19 015 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $500,000 |
| Global Noncommunicable Diseases and Injury Across the Lifespan: Exploratory Research (R21 Clinical Trials Optional) Apply for PAR 19 059 Funding Number: PAR 19 059 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $200,000 |
| Bioengineering Research Partnerships (U01 Clinical Trial Not Allowed) Apply for PAR 19 156 Funding Number: PAR 19 156 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Innovative Approaches for Improving Environmental Health Literacy (R41/R42 Clinical Trial Not Allowed) Apply for RFA ES 19 006 Funding Number: RFA ES 19 006 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Innovative Approaches for Improving Environmental Health Literacy (R43/R44 Clinical Trial Not Allowed) Apply for RFA ES 19 005 Funding Number: RFA ES 19 005 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Transition to Independent Environmental Health Research (TIEHR) Career Award (K01 Independent Basic Experimental Studies with Humans Required) Apply for PAR 19 225 Funding Number: PAR 19 225 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Revolutionizing Innovative, Visionary Environmental health Research (RIVER) (R35 Clinical Trial Not Allowed) Apply for RFA ES 19 007 Funding Number: RFA ES 19 007 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Revolutionizing Innovative, Visionary Environmental health Research (RIVER) (R35 Basic Experimental Studies with Humans Required) Apply for RFA ES 19 008 Funding Number: RFA ES 19 008 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Environmental Influences on Aging: Effects of Extreme Weather and Disaster Events on Aging Processes (R01 Clinical Trial Not Allowed) Apply for PAR 19 249 Funding Number: PAR 19 249 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| SBIR E-Learning for HAZMAT and Emergency Response (R43/R44 Clinical Trial Not Allowed) Apply for RFA ES 19 009 Funding Number: RFA ES 19 009 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Undergraduate Research Education Program (UP) to Enhance Diversity in the Environmental Health Sciences (R25 Clinical Trial Not Allowed) Apply for RFA ES 19 010 Funding Number: RFA ES 19 010 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $100,000 |
| HAZMAT Training at DOE Nuclear Weapons Complex (UH4 Clinical Trial Not Allowed) Apply for RFA ES 19 004 Funding Number: RFA ES 19 004 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $700,000 |
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