Opportunity Information: Apply for PAR 18 755
The NIMH Career Transition Award for Tenure-Track Intramural Investigators (K22, No Independent Clinical Trials) is a National Institute of Mental Health (NIMH) grant program designed to help established intramural investigators at NIMH move from the institute's Division of Intramural Research Programs (DIRP) into independent, tenure-track (or equivalent) faculty positions in the extramural research community. In practical terms, it is meant to support the career step where a successful NIMH intramural researcher leaves NIH to build an independent lab and research program at a university, medical center, or other eligible U.S.-based research organization. The opportunity is specifically framed around investigators who already have a strong track record in mental health-related research and are positioned to make the jump to independence, rather than early trainees who are still establishing their research direction.
The emphasis of the program is career transition and research independence. Applicants are expected to show evidence of meritorious scientific productivity and a compelling plan for continuing and expanding their research outside the intramural NIH environment. Because it is a K22 career transition award, the underlying logic is to provide time and resources that make the move to an extramural faculty role more feasible, while also signaling NIMH's investment in the applicant as an emerging independent investigator in mental health research. This funding opportunity uses the NIH grant mechanism and sits within NIH's health research funding category under CFDA 93.242.
A key limitation is embedded directly in the title: "No Independent Clinical Trials." That designation indicates the award is not intended to support an applicant-led independent clinical trial as part of the K22-supported activities. Applicants can typically still conduct research that is clinically relevant or uses human participants, but they should not propose to serve as the lead for an independent clinical trial within this award mechanism. Anyone considering a project that would cross into independent clinical trial territory would need to look for a different NIH funding pathway or a clinical-trial-appropriate FOA.
Eligibility in the source listing includes a wide range of U.S. organization types that commonly receive NIH funding, including public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (both 501(c)(3) and non-501(c)(3)), for-profit organizations (other than small businesses), and small businesses, as well as other eligible entities described in the full FOA. The announcement also explicitly highlights "Other Eligible Applicants" that include several categories of institutions that serve historically underrepresented or specific populations, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs). Those categories are called out to underscore that these institutions are eligible destinations and participants within the broader extramural community NIMH funds.
The program is limited with respect to foreign involvement. Non-domestic (non-U.S.) entities are not eligible to apply, and non-domestic components of U.S. organizations are also not eligible to apply as the applicant organization. At the same time, "foreign components" as defined in the NIH Grants Policy Statement are allowed, meaning certain parts of a project may involve foreign collaborations or activities when properly justified and structured under NIH policy, even though the applicant institution itself must be U.S.-based. Because the exact boundary between an ineligible non-domestic component and an allowable foreign component can be technical, applicants are directed to the full FOA for complete eligibility details and definitions.
Administratively, the opportunity is a discretionary grant offered by the National Institutes of Health. The Funding Opportunity Number is PAR-18-755, and the listing shows a creation date of April 11, 2018. The source data also references an original closing date of May 7, 2021, which typically means this particular FOA version had a defined application window or has since been superseded, reissued, or closed; anyone intending to apply would need to confirm the current status and any active replacement announcement on NIH/NIMH systems. The provided record does not specify an award ceiling or the expected number of awards, which is another reason to consult the full FOA for budget structure, project period, review criteria, and the mechanics of the transition from intramural to extramural support.
Overall, this K22 is best understood as a targeted bridge for NIMH intramural tenure-track investigators who have demonstrated strong mental health research accomplishments and are ready to establish independent research programs outside NIH, with the constraint that the proposed work should not include an applicant-led independent clinical trial.Apply for PAR 18 755
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "NIMH Career Transition Award for Tenure-Track Intramural Investigators (K22 No Independent Clinical Trials)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242.
- This funding opportunity was created on 2018-04-11.
- Applicants must submit their applications by 2021-05-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Public and State controlled institutions of higher education, Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Applicants also applied for:
Applicants who have applied for this opportunity (PAR 18 755) also looked into and applied for these:
| Funding Opportunity |
|---|
| Development of Curricular or Training Activities in Skills Development (Admin Supp Clinical Trial Not Allowed) Apply for PA 18 759 Funding Number: PA 18 759 Agency: National Institutes of Health Category: Health Funding Amount: $80,000 |
| Development of Curricular or Training Activities in Laboratory Safety (Admin Supp Clinical Trial Not Allowed) Apply for PA 18 758 Funding Number: PA 18 758 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Development of Curricular or Training Activities in Rigor and Transparency to Enhance Reproducibility (Admin Supp Clinical Trial Not Allowed) Apply for PA 18 756 Funding Number: PA 18 756 Agency: National Institutes of Health Category: Health Funding Amount: $80,000 |
| Administrative Supplements to NIGMS Predoctoral Training Grants for the Development of Activities to Prepare Trainees for Careers in the Biomedical Research Workforce (Admin Supp Clinical Trial Not Allowed) Apply for PA 18 757 Funding Number: PA 18 757 Agency: National Institutes of Health Category: Health Funding Amount: $80,000 |
| Novel Nucleic Acid Sequencing Technology Development (R01 Clinical Trial Not Allowed) Apply for RFA HG 18 001 Funding Number: RFA HG 18 001 Agency: National Institutes of Health Category: Health Funding Amount: $700,000 |
| Novel Nucleic Acid Sequencing Technology Development (R43/R44 Clinical Trial Not Allowed) Apply for RFA HG 18 003 Funding Number: RFA HG 18 003 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Novel Nucleic Acid Sequencing Technology Development (R21 Clinical Trial Not Allowed) Apply for RFA HG 18 002 Funding Number: RFA HG 18 002 Agency: National Institutes of Health Category: Health Funding Amount: $200,000 |
| In Vivo Synaptic Function in Alzheimers Disease and Related Dementias (R21 Clinical Trial Not Allowed) Apply for PAR 18 760 Funding Number: PAR 18 760 Agency: National Institutes of Health Category: Health Funding Amount: $200,000 |
| Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Neurotherapeutic Agent Characterization and In vivo Efficacy Studies (R61/R33 Clinical Trial Not Allowed) Apply for PAR 18 761 Funding Number: PAR 18 761 Agency: National Institutes of Health Category: Health Funding Amount: $499,000 |
| Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Development and Validation of Model Systems and/or Pharmacodynamic Markers to Facilitate Neurotherapeutic Discovery (R61/R33 Clinical Trial Not Allowed) Apply for PAR 18 763 Funding Number: PAR 18 763 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Assay Development and Neurotherapeutic Agent Identification (R61/R33 Clinical Trial Not Allowed) Apply for PAR 18 762 Funding Number: PAR 18 762 Agency: National Institutes of Health Category: Health Funding Amount: $499,000 |
| Targeted In Vivo Delivery of Gene Therapeutics for HIV Cure (R01 Clinical Trial Not Allowed) Apply for RFA AI 18 016 Funding Number: RFA AI 18 016 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Small Research Grant Program for the Next Generation of Researchers in Basic Alzheimer's Disease (AD) and Alzheimers Disease Related Dementias (ADRD) Research (R03 Clinical Trial Not Allowed) Apply for RFA AG 19 003 Funding Number: RFA AG 19 003 Agency: National Institutes of Health Category: Health Funding Amount: $100,000 |
| Small Research Grant Program for the Next Generation of Clinical Researchers in Alzheimer's Disease (AD) and Alzheimers Disease Related Dementias (ADRD) Research (R03 Clinical Trial Optional) Apply for RFA AG 19 002 Funding Number: RFA AG 19 002 Agency: National Institutes of Health Category: Health Funding Amount: $100,000 |
| Advancing HIV Therapeutic Vaccine Science (U01 Clinical Trial Required) Apply for RFA AI 18 015 Funding Number: RFA AI 18 015 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| T32 Training Program for Institutions That Promote Diversity (T32 Clinical Trial Not Allowed) Apply for RFA HL 19 023 Funding Number: RFA HL 19 023 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Improving the Reach and Quality of Cancer Care in Rural Populations (R01 Clinical Trial Required) Apply for RFA CA 18 026 Funding Number: RFA CA 18 026 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| AHRQ Health Services Research Dissertation Program (R36) Apply for PA 18 765 Funding Number: PA 18 765 Agency: Agency for Health Care Research and Quality Category: Health Funding Amount: $40,000 |
| Catalyzing Innovation in Late Phase Clinical Trial Design and Statistical Analysis Plans (U34 Clinical Trial Not Allowed) Apply for RFA HL 19 027 Funding Number: RFA HL 19 027 Agency: National Institutes of Health Category: Health Funding Amount: $125,000 |
| Catalyzing Innovation in Late Phase Clinical Trial Design and Statistical Analysis Plans Resource Access (X01 Clinical Trial Not Allowed) Apply for PAR 18 768 Funding Number: PAR 18 768 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
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